Lab members

Lucas Schirmer, MD

Lucas is a physician-scientist focusing on disease mechanisms in acute and chronic neuroinflammation with an emphasis on MS and demyelinating diseases.

He studied medicine at the University of Göttingen, followed by clinical training in Neurology at Technical University of Munich and postdoctoral studies at the University of California, San Francisco and the University of Cambridge.

More recently, his research expanded to experimental models and systems biology using complex transgenic mouse models and single-cell RNA-sequencing technologies in the context of neuroinflammation.

His clinical interests are circled around immune-mediated peripheral and central nervous system diseases.

Tatjana Beutel, MD

Tatjana studied medicine at the University of Bonn and is a physician-scientist. She regularly combines clinical training in Neurology with translational MS research. Her scientific interests are on neuron subtype functions and selective vulnerabilities in progressive MS. Her clinical focus is on immune-mediated neurological diseases with an emphasis on MS and related demyelinating disorders of the central nervous system.

 

tatjana.beutel@medma.uni-heidelberg.de

Julia Dyckow, DVM

Julia studied veterinary medicine at the Ludwig Maximilian University of Munich. She is a PhD student in the lab focusing on experimental model systems and glial subtype-specific mechanisms during inflammatory demyelination. Julia has a major interest in utilizing complex transgenic model systems in combination with high-resolution imaging to dissect glial subtype functions during disease progression under inflammatory-demyelinating conditions.

 

 

julia.dyckow@medma.uni-heidelberg.de

Niklas Grassl, MD

Niklas studied medicine at Technical University of Munich and is a physician-scientist combining clinical training in Neurology with wet and dry lab work. His scientific focus is on deconvoluting immune-mediated mechanisms in glioma and autoimmune demyelination. Niklas regularly utilizes cutting-edge high-dimensional proteomic approaches to dissect cell type-specific proteomics in combination with RNA-sequencing. His ultimate goals are a better understanding of the compartmentalized immune-mediated pathologies in MS and glioma.

 

 

niklas.grassl@medma.uni-heidelberg.de

Annika Hofmann, cand. med.

Annika is a medical student at the Medical Faculty in Mannheim with a strong scientific focus on myeloid cell subtypes as drivers of disease progression under inflammatory-demyelinating conditions such as MS. In her thesis project, she utilizes high-resolution and large-area spatial transcriptomics to decode myeloid cell subtype diversity in MS.

 

annika.hofmann@stud.uni-heidelberg.de

Hannah Kapell, cand. med.

Hannah studies medicine at the Medical Faculty in Heidelberg and focuses in her doctoral thesis on neuron subtypes and their response patterns towards inflammatory demyelination. She utilizes complex experimental model systems in combination with cutting-edge cell-type specific RNA-sequencing technologies to answer questions related to neuron subtype vulnerabilities in MS and related model systems.

 

Hannah is supported by scholarships of the German Academic Scholarship Foundation and the Hertie Foundation (medMS doctorate program).

 

kapell@stud.uni-heidelberg.de

 

Michael Kutza, cand. med.

Michael is a medical student at the Medical Faculty in Mannheim and has a strong scientific interest in dissecting cell-type specific neuroimmune diversity in inflamed tissue niches in MS and neuroinfectious diseases. To address these questions, Michael utilizes several cutting-edge cell-type specific RNA-sequencing techniques in combination with high-performance computing and spatial transcriptomics.

 

Michael is supported by a medMS Hertie Foundation scholarship.

 

 

kutza@stud.uni-heidelberg.de

Celia Lerma Martin, M.Sc.

Celia studied biology at the Autonomous University of Barcelona and is a PhD student in the lab. She combines wet with dry lab work developing and implementing novel cell type-specific genomic technologies to decipher molecular key drivers in neuroinflammation. She has a particular interest in how immune cells interact with neuron subtypes during different inflammatory stages.

 

Celia is a member of the Heidelberg Biosciences International Graduate School (HBIGS).

 

celia.lermamartin@medma.uni-heidelberg.de

Mikail Öztürk, cand. med.

Mikail studies medicine at the Medical Faculty in Mannheim and is highly interested in understanding cell-type specific mechanisms that drive disease progression in MS and other neurodegenerative diseases. In particular, his focus is on afferent systems and how sensory neuron subtype functions are dysregulated under chronic inflammatory-demyelinating conditions.

 

Mikail is supported by a scholarship of the German Academic Scholarship Foundation.

 

oeztuerk@stud.uni-heidelberg.de

 

Nadja Pfirmann, cand. med.

Nadja is a medical student at the Medical Faculty in Mannheim and focuses in her doctoral thesis on immune-mediated neuropathies. She has a strong interest in overlapping neurological features in rheumatological diseases and is co-supervised by Hans-Werner.

Hans-Werner Rausch, MD

Hans-Werner studied medicine at the Medical Faculty in Heidelberg and is a physician-scientist and specialist Neurologist. His scientific interests are on immune-mediated mechanisms of neuromuscular diseases such as myositis and neuropathies. In particular, he is interested in rheumatological overlap syndromes and shared pathological mechanisms.

His clinical focus is complementary and circled around immune-mediated diseases of the peripheral nervous system. 

 

hans-werner.rausch@umm.de

Sophia Schwarz, cand. med.

Sophia is a medical student at the Medical Faculty in Mannheim and focuses in her thesis project on cell-type specific pathologies along the anterior visual system in MS. She utilizes large-area and high-resolution imaging techniques in combination with multiplex spatial transcriptomics to deconvolute neuroimmune dysfunction. 

 

Sophia is supported by a scholarship of the German Government.

 

sophia.schwarz@stud.uni-heidelberg.de

Tim Trobisch, cand. med.

Tim studies medicine at the Medical Faculty in Mannheim and has a strong interest in decoding cell-type specific molecular states in immune-mediated pathologies such as MS and glioma. To dissect these pathologies, Tim utilizes high-performance computing and cutting-edge bioinformatics and validates findings with the help of multiplex spatial transcriptomics. 

 

Tim is supported by a scholarship of the German Cancer Aid.

 

trobisch@stud.uni-heidelberg.de

Sven Wischnewski, cand. med.

Sven is a medical student at the Medical Faculty in Mannheim and has major scientific focus on immune-mediated myopathies. He regularly uses cutting-edge cell type-specific RNA-sequencing technologies in combination with high-resolution imaging to understand and decipher molecular key drivers of pathology in myositis. He also has a strong interest in overlapping transcriptomic features in MS and related diseases of the central nervous system. 

 

Sven is supported by a scholarship of the Medical Faculty Mannheim.

 

s.wischnewski@stud.uni-heidelberg.de

Amel Zulji, M.Sc.

Amel studied molecular biology at the University of Zagreb and is a PhD student in the lab. He combines wet with dry lab work and aims at decoding cell type-specific molecular states in compartmentalized inflammatory-demyelinating diseases such as MS. Amel routinely uses high-performance computing and cutting-edge bioinformatics to address these questions. By integrating single-cell genomics data from different lesion stages and areas, he aims at breaking the code underlying disease progression in MS.

 

Amel is a member of the Heidelberg Biosciences International Graduate School (HBIGS).

 

amel.zulji@medma.uni-heidelberg.de