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Friedrich M, Sankowski R, Bunse L, Kilian M, Green E, Ramallo Guevara C, Pusch S, Poschet G, Sanghvi K, Hahn M, Bunse T, Münch P, Gegner HM, Sonner JK, von Landenberg A, Cichon F, Aslan K, Trobisch T, Schirmer L, Abu-Sammour D, Kessler T, Ratliff M, Schrimpf D, Sahm F, Hopf C, Heiland DH, Schnell O, Beck J, Böttcher C, Fernandez-Zapata C, Priller J, Heiland S, Gutcher I, Quintana FJ, von Deimling A, Wick W, Prinz M, Platten M. Tryptophan metabolism drives dynamic immunosuppressive myeloid states in IDH-mutant gliomas. Nature Cancer. 2021. May.


Heintz A, Sold S, Wühler F, Dyckow J, Schirmer L, Beuermann T, Rädle M. Design of a Multimodal Imaging System and Its First Application to Distinguish Grey and White Matter of Brain Tissue. A Proof-of-Concept-Study. Appl. Sci. 2021. 11(11), 4777;


Sessler K, Blechschmidt V, Hoheisel U, Mense S, Schirmer L, Treede RD. Spinal cord fractalkine (CX3CL1) signaling is critical for neuronal sensitization in experimental non-specific, myofascial low back pain. J Neurophysiol. 2021 Feb 17. PMID: 33596743


Schirmer L, Schafer DP, Bartels T, Rowitch DH, Calabresi PA. Diversity and Function of Glial Cell Types in Multiple Sclerosis. Trends Immunol. 2021 Feb 13:S1471-4906(21)00005-3. PMID: 33593693


Paredes I, Vieira JR, Shah B, Ramunno CF, Dyckow J, Adler H, Richter M, Schermann G, Giannakouri E, Schirmer L, Augustin HG, Ruiz de Almodóvar C. Oligodendrocyte precursor cell specification is regulated by bidirectional neural progenitor-endothelial cell crosstalk. Nat Neurosci. 2021 Jan 28. PMID: 33510480


Fuchs V, Kutza M, Wischnewski S, Deigendesch N, Lutz L, Kulsvehagen L, Ricken G, Kappos L, Tzankov A, Hametner S, Frank S, Schirmer L, Pröbstel AK. Presence of SARS-CoV-2 Transcripts in the Choroid Plexus of MS and Non-MS Patients With COVID-19. Neurol Neuroimmunol Neuroinflamm. 2021 Jan 27;8(2):e957. PMID: 33504636


Kim K, Pröbstel AK, Baumann R, Dyckow J, Landefeld J, Kogl E, Madireddy L, Loudermilk R, Eggers EL, Singh S, Caillier SJ, Hauser SL, Cree BAC; UCSF MS-EPIC Team, Schirmer L, Wilson MR, Baranzini SE. Cell type-specific transcriptomics identifies neddylation as a novel therapeutic target in multiple sclerosis. Brain. 2020 Dec 29:awaa421. PMID: 33374005


Pröbstel AK, Zhou X, Baumann R, Wischnewski S, Kutza M, Rojas OL, Sellrie K, Bischof A, Kim K, Ramesh A, Dandekar R, Greenfield AL, Schubert RD, Bisanz JE, Vistnes S, Khaleghi K, Landefeld J, Kirkish G, Liesche-Starnecker F, Ramaglia V, Singh S, Tran EB, Barba P, Zorn K, Oechtering J, Forsberg K, Shiow LR, Henry RG, Graves J, Cree BAC, Hauser SL, Kuhle J, Gelfand JM, Andersen PM, Schlegel J, Turnbaugh PJ, Seeberger PH, Gommerman JL, Wilson MR, Schirmer L, Baranzini SE. Gut microbiota–specific IgA+ B cells traffic to the CNS in active multiple sclerosis. Sci Immunol. 2020 Nov 20;5(53):eabc7191. PMID: 33219152


Beutel T, Dzimiera J, Kapell H, Engelhardt M, Gass A, Schirmer L. Cortical projection neurons as a therapeutic target in multiple sclerosis. Expert Opin Ther Targets. 2020 Oct 24. PMID: 33103501


Deigendesch N, Sironi L, Kutza M, Wischnewski S, Fuchs V, Hench J, Frank A, Nienhold R, Mertz KD, Cathomas G, Matter MS, Siegemund M, Tolnay M, Schirmer L, Pröbstel AK, Tzankov A, Frank S. Correlates of critical illness-related encephalopathy predominate postmortem COVID-19 neuropathology. Acta Neuropathol. 2020 Oct;140(4):583-586. PMID: 32851506


Bergmann N, Delbridge C, Gempt J, Feuchtinger A, Walch A, Schirmer L, Bunk W, Aschenbrenner T, Liesche-Starnecker F, Schlegel J. The Intratumoral Heterogeneity Reflects the Intertumoral Subtypes of Glioblastoma Multiforme: A Regional Immunohistochemistry Analysis. Front Oncol. 2020 Apr 24;10:494. PMID: 32391260


Schirmer L, Velmeshev D, Holmqvist S, Kaufmann M, Werneburg S, Jung D, Vistnes S, Stockley JH, Young A, Steindel M, Tung B, Goyal N, Bhaduri A, Mayer S, Engler JB, Bayraktar OA, Franklin RJM, Haeussler M, Reynolds R, Schafer DP, Friese MA, Shiow LR, Kriegstein AR, Rowitch DH.Neuronal vulnerability and multilineage diversity in multiple sclerosis. Nature. 2019 Sep;573(7772):75-82. PMID: 31316211.


Lanz TV, Pröbstel AK, Mildenberger I, Platten M, Schirmer L. Single-cell high-throughput technologies in cerebrospinal fluid research and diagnostics. Front Immunol. 2019 Jun 11;10:1302. PMID: 31244848


Velmeshev D, Schirmer L, Jung D, Haeussler M, Perez Y, Mayer S, Bhaduri A, Goyal N, Rowitch DH, Kriegstein AR. Single-Cell Genomics Identifies Cell Type-Specific Molecular Changes in Autism. Science. 2019 May 17;364(6441):685-689. PMID: 31097668.


Gempt J, Bette S, Albertshauser J, Järschke J, Gradtke C, Schirmer L, Ryang YM, Meyer B, Ringel F. Personality Traits in Patients with Neuroepithelial Tumors – A Prospective Study. Sci Rep. 2018 Nov 19;8(1):17055. PMID: 30451871.


Berndt M, Friedrich B, Maegerlein C, Mönch C, Hedderich D, Lehm M, Zimmer C, Straeter A, Poppert H, Wunderlich S, Schirmer L, Oberdieck P, Kaesmacher J, Boeckh-Behrens T. Thrombus permeability in admission CT imaging indicates stroke etiology based on thrombus histology. Stroke. 2018 Nov;49(11):2674-2682. PMID: 30355200.


Schirmer L, Möbius W, Zhao C, Cruz-Herranz A, Ben Haim L, Cordano C, Shiow LR, Kelley KW, Sadowski B, Timmons G, Pröbstel AK, Wright JN, Sin JH, Devereux M, Morrison DE, Chang SM, Sabeur K, Green A, Nave KA, Franklin RJ, Rowitch DH. Oligodendrocyte-encoded Kir4.1 function is required for axonal integrity. Elife. 2018 Sep 11; 7. PMID: 30204081.


Kelley KW, Ben Haim L, Schirmer L, Tyzack GE, Tolman M, Miller JG, Tsai HH, Chang SM, Molofsky AV, Yang Y, Patani R, Lakatos A, Ullian EM, Rowitch DH. Kir4.1-Dependent Astrocyte-Fast Motor Neuron Interactions Are Required for Peak Strength. Neuron. 2018 Mar 28. PMID: 29606582.


Berndt M, Prothmann S, Maegerlein C, Oberdieck P, Zimmer C, Hegge B, Pelisek J, Schirmer L, Poppert H, Boeckh-Behrens T. Artificial Stroke Clots: How Wide is the Gap to the Real World? World Neurosurg. 2018 Feb; 110:e90-e99. PMID: 29107162.


Maegerlein C, Friedrich B, Berndt M, Lucia KE, Schirmer L, Poppert H, Zimmer C, Pelisek J, Boeckh-Behrens T, Kaesmacher J. Impact of histological thrombus composition on preinterventional thrombus migration in patients with acute occlusions of the middle cerebral artery. Interv Neuroradiol. 2018 Feb; 24(1):70-75. PMID: 29058984.


Shiow LR, Favrais G, Schirmer L, Schang AL, Cipriani S, Andres C, Wright JN, Nobuta H, Fleiss B, Gressens P, Rowitch DH. Reactive astrocyte COX2-PGE2 production inhibits oligodendrocyte maturation in neonatal white matter injury. Glia. 2017 Dec; 65(12):2024-2037. PMID: 28856805.


Wirth M, Schirmer L, Hofauer B, Lenschow M, Loos D, Thuermel K, Knopf A. Head and neck giant cell arteritis: an autoimmune disease with many faces. Acta Otolaryngol. 2017 Sep; 137(9):986-991. PMID: 28440088.


Boeckh-Behrens T, Kleine J, Kaesmacher J, Zimmer C, Schirmer L, Simon S, Poppert H. The CD31 molecule: a possible neuroprotective agent in acute ischemic stroke? Thromb J. 2017; 15:11. PMID: 28413360.


Sabo JK, Heine V, Silbereis JC, Schirmer L, Levison SW, Rowitch DH. Olig1 is required for noggin-induced neonatal myelin repair. Ann Neurol. 2017 Apr; 81(4):560-571. PMID: 28253550.


Kaesmacher J, Boeckh-Behrens T, Simon S, Maegerlein C, Kleine JF, Zimmer C, Schirmer L, Poppert H, Huber T. Risk of Thrombus Fragmentation during Endovascular Stroke Treatment. AJNR Am J Neuroradiol. 2017 May; 38(5):991-998. PMID: 28279987.


Liddelow SA, Guttenplan KA, Clarke LE, Bennett FC, Bohlen CJ, Schirmer L, Bennett ML, Münch AE, Chung WS, Peterson TC, Wilton DK, Frouin A, Napier BA, Panicker N, Kumar M, Buckwalter MS, Rowitch DH, Dawson VL, Dawson TM, Stevens B, Barres BA. Neurotoxic reactive astrocytes are induced by activated microglia. Nature. 2017 01 26; 541(7638):481-487. PMID: 28099414.


Schirmer L, Worthington V, Solloch U, Loleit V, Grummel V, Lakdawala N, Grant D, Wassmuth R, Schmidt AH, Gebhardt F, Andlauer TF, Sauter J, Berthele A, Lunn MP, Hemmer B. Higher frequencies of HLA DQB1*05:01 and anti-glycosphingolipid antibodies in a cluster of severe Guillain-Barré syndrome. J Neurol. 2016 Oct; 263(10):2105-13. PMID: 27485170.


Boeckh-Behrens T, Kleine JF, Zimmer C, Neff F, Scheipl F, Pelisek J, Schirmer L, Nguyen K, Karatas D, Poppert H. Thrombus Histology Suggests Cardioembolic Cause in Cryptogenic Stroke. Stroke. 2016 07; 47(7):1864-71. PMID: 27197854.


Schirmer L, Wölfel S, Georgi E, Ploner M, Bauer B, Hemmer B. Extensive Recruitment of Plasma Blasts to the Cerebrospinal Fluid in Toscana Virus Encephalitis. Open Forum Infect Dis. 2015 Sep; 2(3):ofv124. PMID: 26393235.


Central Boeckh-Behrens T, Schubert M, Förschler A, Prothmann S, Kreiser K, Zimmer C, Riegger J, Bauer J, Neff F, Kehl V, Pelisek J, Schirmer L, Mehr M, Poppert H. The Impact of Histological Clot Composition in Embolic Stroke. Clin Neuroradiol. 2016 Jun; 26(2):189-97. PMID: 25261075.


Schirmer L, Srivastava R, Kalluri SR, Böttinger S, Herwerth M, Carassiti D, Srivastava B, Gempt J, Schlegel J, Kuhlmann T, Korn T, Reynolds R, Hemmer B. Differential loss of KIR4.1 immunoreactivity in multiple sclerosis lesions. Ann Neurol. 2014 Jun; 75(6):810-28. PMID: 24777949.


Schirmer L, Srivastava R, Hemmer B. To look for a needle in a haystack: the search for autoantibodies in multiple sclerosis. Mult Scler. 2014 Mar; 20(3):271-9. PMID: 24589684.


Schirmer L, Rothhammer V, Hemmer B, Korn T. Enriched CD161high CCR6+ γd T cells in the cerebrospinal fluid of patients with multiple sclerosis. JAMA Neurol. 2013 Mar 01; 70(3):345-51. PMID: 23599932.


Srivastava R, Aslam M, Kalluri SR, Schirmer L, Buck D, Tackenberg B, Rothhammer V, Chan A, Gold R, Berthele A, Bennett JL, Korn T, Hemmer B. Potassium channel KIR4.1 as an immune target in multiple sclerosis. N Engl J Med. 2012 Jul 12; 367(2):115-23. PMID: 22784115.


Schirmer L, Merkler D, König FB, Brück W, Stadelmann C. Neuroaxonal regeneration is more pronounced in early multiple sclerosis than in traumatic brain injury lesions. Brain Pathol. 2013 Jan; 23(1):2-12. PMID: 22612622.


Lahmer T, Küchle C, Schirmer L, Heemann U, Lutz J, Thürmel K. Kidney transplant after preexisting posterior reversible encephalopathy syndrome induced by Goodpasture's syndrome. Exp Clin Transplant. 2012 Jun; 10(3):299-301. PMID: 22631071.


Sellner J, Schirmer L, Erik Gilhus N, Grisold W, Struhal W. The Open Facilities for Training in European Neurology (OFTEN): an emerging pan-European exchange programme for junior neurologists. Eur J Neurol. 2012 Jun; 19(6):e54-5. PMID: 22448868.


Schirmer L, Seifert CL, Pfeifenbring S, Wunderlich S, Stadelmann C, Hemmer B. Clinicopathological considerations in acute disseminated encephalomyelitis (ADEM): a fulminant case with favorable outcome. J Neurol. 2012 Apr; 259(4):753-5. PMID: 21901482.


Schirmer L, Antel JP, Brück W, Stadelmann C. Axonal loss and neurofilament phosphorylation changes accompany lesion development and clinical progression in multiple sclerosis. Brain Pathol. 2011 Jul; 21(4):428-40. PMID: 21114565.


Sellner J, Schirmer L, Hemmer B, Mühlau M. [Radiologically isolated syndrome: multiple sclerosis based solely on MRI findings?]. Nervenarzt. 2010 Oct; 81(10):1208-17. PMID: 20422146.


Sellner J, Schirmer L, Hemmer B, Mühlau M. The radiologically isolated syndrome: take action when the unexpected is uncovered? J Neurol. 2010 Oct; 257(10):1602-11. PMID: 20503053.


Schirmer L, Albert M, Buss A, Schulz-Schaeffer WJ, Antel JP, Brück W, Stadelmann C. Substantial early, but nonprogressive neuronal loss in multiple sclerosis (MS) spinal cord. Ann Neurol. 2009 Nov; 66(5):698-704. PMID: 19938172.